Expert: popular weight loss supplements turned out to be useless

      Denis Borozdenko, assistant professor of the pharmacology department at the Pirogov University Institute of Pharmacy and Medical Chemistry (IFMХ), junior research fellow in the medical chemistry and toxicology department of IFMХ, explained how popular dietary supplements actually work.

      Chlorophyll: beautiful color with weak evidence

      Chlorophyll is a plant pigment responsible for the green color of leaves and stems. In dietary supplements, its semi-synthetic analogue – chlorophyllin – is used, which is more stable and water-soluble. However, as Denis Borozdenko explains, there is virtually no scientific evidence for the targeted healing effects of chlorophyll on the body.

      Some data on antioxidant activity exists, but it has been obtained exclusively in laboratory experiments on cell cultures, not in studies on animals or volunteers. In combination with other components of greens (fiber, vitamins, minerals), chlorophyll may contribute to improved bowel function and have a general strengthening effect – for example, with high consumption of greens as part of a Mediterranean diet.

      Impact on weight: only as part of a balanced diet

      This suggests that taking isolated dietary supplements with chlorophyll does not yield a pronounced effect. Positive changes in appearance, including weight loss, are achievable only with a balanced diet (including green products with chlorophyll) and sufficient physical activity.

      Chlorophyll overdose from consuming plant foods is virtually impossible; however, uncontrolled intake of supplements can lead to side effects. The first signs of excess are changes in the color of urine and stool – these are the complaints patients often bring to their doctor.

      Magnesium citrate: benefits for nerves, but not for fat

      Magnesium citrate is a popular and easily absorbed form of magnesium, bound to citric acid. It is a critically important trace element necessary for the functioning of the nervous system and gastrointestinal tract. However, its direct influence on the weight loss process remains in question.

      From a pharmacological perspective, magnesium acts as a mild laxative. For example, medicinal mineral water rich in magnesium is the first-choice treatment for functional constipation. Magnesium does not have fat-splitting properties. For the central nervous system, magnesium is valuable for its ability to normalize sleep and reduce stress levels. It is also important to remember the harm of excessively large doses: diarrhea and sleep disturbances are possible.

      Thus, both chlorophyll (in green products) and magnesium citrate can become useful components of an overall health program that accompanies the weight loss process. They can improve sleep, digestion, and help in the fight against stress, which, in turn, facilitates adherence to the main rules: proper nutrition and regular exercise. These substances alone are not fat burners.